The composition of propolis can vary depending on the location of the bees and what trees and flowers they have access to. For example, propolis from Europe won’t have the same chemical makeup as propolis from Brazil.

Researchers have identified more than 300 compounds in propolis. The majority of these compounds are forms of polyphenols. Polyphenols are antioxidants that fight disease and damage in the body. Propolis has a special compound called pinocembrin, a flavonoid that acts as an antifungal. These anti-inflammatory and antimicrobial properties make propolis helpful in wound healing, cold sores, and genital herpes.